Study of an investigational device system for removing blood clots from the brains of subjects with blockage of blood flow to one of the arteries in the brain

Stroke most commonly occurs when there is a blockage of blood flow to one of the arteries in the brain. The blockage is often caused by a blood clot. This is called an ischemic stroke. The purpose of this study is to determine the safety and effectiveness of an experimental device system in the removal of blood clots in the brain. Currently, there are limited treatments for ischemic stroke. The knowledge gained from this study may be of benefit to the advancement of medical treatment for ischemic stroke.

You may be eligible to participate in this study if you:

• Display clinical signs of a blockage of blood flow to the brain, such as numbness or weakness of face or extremities, sudden confusion, trouble speaking or understanding speech, sudden trouble walking, dizziness, or loss of balance
• Arrived at the hospital within 8 hours of stroke symptom onset

You will be excluded from this study if you have:

• Rapidly improving signs of stroke at time of enrollment

Note: This study is only for patients admitted to the hospital with onset of stroke symptoms.